Immunoregulation in humans: control of antitetanus toxoid antibody production after booster immunization.

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Immunoregulation in humans: control of antitetanus toxoid antibody production after booster immunization.

Booster immunization of normal individuals with soluble tetanus toxoid resulted in the ability of the individuals' peripheral blood lymphocytes to synthesize immunoglobulin (Ig)G antitetanus toxoid antibody in vitro when stimulated by pokeweed mitogen. The capacity for this in vitro antitetanus toxoid antibody response developed within 14 days after booster immunization, reached a peak between ...

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ژورنال

عنوان ژورنال: Journal of Clinical Investigation

سال: 1978

ISSN: 0021-9738

DOI: 10.1172/jci109234